University of Minnesota
University of Minnesota
College of Biological Sciences

Center for Mass Spectrometry and Proteomics

The Center for Mass Spectrometry and Proteomics (CMSP) facility is a subunit of the Department of Biochemistry, Molecular Biology and Biophysics (BMBB). The CMSP provides support, equipment, and expertise for analyzing complex protein mixtures. Mass spectrometric data can provide intact protein molecular weight as well as protein identification by peptide mass fingerprint or MS/MS data, combined with protein database searching. In addition, some mass spectrometers provide accurate mass measurement for organic molecules and relative protein quantification via isotope labeling techniques (e.g., iTRAQ™).

The center also has equipment to help with complex protein separation and differential expression of protein between two samples. The facility has the capability of traditional 2D SDS-PAGE, DIGE and high throughput spot picking, digestion, and desalting.

Publications with CMSP authorship, acknowledgement or instrument usage

MS-based bioinformatics Post doc position available (T Griffin lab): link to job posting

Click here to access CMSP Proteomics Workshop Website

Next Proteomics Workshop: August 12 - 24, 2014

The workshops involve lectures, hands-on instrument experience and discussions of critical aspects of MS-baed proteomic analyses, including: experimental design, sample preparation, protein preparation for MS identification, liquid chromatography, mass spec data acquisition and mass spec data analysis. Workshops include practical applications of gel-based protein separation, including 1D & 2D gel separation, DIGE technology and non-gel based protein preparation. Individuals will observe MS data acuisition on a variety of instruments with multiple ionization sources (MALDI, ESI) and multiple scan modes (MS, MS/MS, MSn).























Data Access via TINT


Contact Information

Main Phone

(612) 624-7715

CMSP-St.Paul (Map)


(Shipping address)
University of Minnesota
43 Gortner Laboratory
1479 Gortner Avenue
St. Paul, MN 55108



Campus Mailing Address:
140 Gortner Laboratory
1479 Gortner Avenue
St. Paul, MN 55108

Phone: (612) 625-2280
Fax: (612) 625-5780


Sample Preparation Lab:
46 Gortner Laboratory


CMSP-Minneapolis (Map)

(Shipping address)
University of Minnesota
5-194 MCB
420 Washington Ave.
Minneapolis, MN 55455
Campus Mailing Address
6-155 Jackson Hall
321 Church Street NE
Minneapolis, MN 55455

Phone: (612) 625-2279

Phone: (612) 624-2674
Fax: (612) 625-2163

UM Printable Campus Maps

Email: webmaster