University of Minnesota
University of Minnesota
College of Biological Sciences
http://www.cbs.umn.edu/

Wackett Lab

Research Overview

The Wackett laboratory studies microbial enzymes and pathways for biocatalysis and biodegradation and helped build the Biocatalysis/Biodegradation Database.

Biodegradation

  • Atrazine – Biocatalyst encapsulation and water treatment
  • Cyanuric acid – Removal from swimming pool water
  • Acrylamide – Treatment in foods and waters
  • Aromatic hydrocarbons – Modeling and mechanisms

Biocatalysis

  • Hydrocarbon biosynthesis – Enzyme structure and mechanisms
  • Enzyme-based sensors for detecting toxicants

New Projects

  • Biodegradation relevant to hydraulic fracturing (fracking)
  • Predicting biodegradation potential of enzymes and microbes

News Highlights

Atrazine - Manufacturing of bioreactive nanofibers for bioremediation – Tong, et al 2014

Cyanuric acid hydrolase - Paper in press – Cho, et al 2014, Crystal structure, PLOS ONE

Polycyclic Aromatic Hydrocarbon (PAH) oxidation – Paper in press - Aukema, et al, 2014

Predicting biodegradation potential – New grant award with Professor Al Aksan

Bioremediation startup founded  – Minnepura Technologies, Inc.