strain CM- 2. Biochemistry 36(8):2147-2153.

Newman, L.M. and L.P. Wackett (1997) Trichloroethylene oxidation by purified toluene 2-monooxygenase: Products, kinetics and turnover-dependent inactivation. J. Bacteriol. 179(1):90-96.

Ellis, L. B. M. and L.P. Wackett (1997) The University of Minnesota Biocatalysis/Biodegradation Database on the World Wide Web. WWW .

Wackett, L.P. (1997) Bacterial biocatalysis: Stealing a page from nature's book. Nature Biotechnology 15(5):415-416.

Lange, C. C. and L.P. Wackett (1997) Oxidation of aliphatic olefins by toluene dioxygenase: Enzyme rates and product identification. J. Bacteriol. 179(12):3858-3865.

Ellis, L.B.M. and L.P. Wackett (1997) Microbial biocatalysis and biodegradation informatics. Nature Biotechnology 15(12):1406.

Wackett, L. P., C. L. Lange and R. L. Ornstein (1997) Optimizing biodegradation: Search, select, assemble and systematize. In R. L. Ornstein, ed., Hanford Symposium on Health and the Environment 289-298.

Wackett, L.P. (1997) Designing metabolic pathways for the biodegradation of halogenated compounds In S.K. Sikdar, ed. Bioremediation: Principles and Practice, Technomics Publishers, Basel. 435-456.

Wackett, L.P. (1997) Biocatalysis, biodegradation, and bioinformatics. J. Ind. Microbiol. Biotechnol. 19:350-354.

M.L. deSouza, D. Newcombe, S. Alvey, Crowley, D.E., A. Hay, M.J. Sadowsky, and L.P. Wackett (1998) Molecular basis of a bacterial consortium: Interspecies catabolism of atrazine. Appl. Environ. Microbiol. 64(1):178-184.

Sadowsky, M.J., M.L. DeSouza, Z. Tong, and L.P. Wackett (1998) AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes. J. Bacteriol. 180:152-158.

M.J. Sadowsky, L.P. Wackett, M.L. deSouza, K.L. Boundy-Mills, and R. T. Mandelbaum (1998) Genetics of atrazine degradation in Pseudomonas sp. strain ADP In L. Ballantine, J. McFarland, D. Hackett, eds., American Chemical Society Symposium Series. .

Wackett, L. P., M. J. Sadowsky, M. L. de deSouza, and R. T. Mandelbaum (1998) Enzymatic hydrolysis of atrazine In L. Ballantine, J. McFarland, D. Hackett, eds., American Chemical Society Symposium Series. .

DeSouza, M. L., J. Seffernick, B. Martinez, and M. J. Sadowsky, L. P. Wackett (1998) Atrazine catabolism genes atzABC are widespread and highly conserved J. Bacteriol. 180(1):1951-1954.

De deSouza, M. L., L. P. Wackett, and M. J. Sadowsky (1998) The atzABC genes encoding atrazine catabolism are located on a self-transmissible plasmid in Pseudomonas sp. strain ADP. Appl. Envir. Microbiol. 64(6):2323-2326.

M.J. Sadowsky, L.P. Wackett, M.L.deSouza, K.L. Boundy-Mills, and R. T. Mandelbaum (1998) Genetics of atrazine degradation in Pseudomonas sp. strain ADP In L. Ballantine, J. McFarland, D. Hackett, eds., Triazine Herbicides: Risk Assessment, American Chemical Society Symposium Series vol. 683, p. 88-94.

Wackett, L. P., M. J. Sadowsky, M. L. de deSouza, and R. T. Mandelbaum (1998) Enzymatic hydrolysis of atrazine In L. Ballantine, J. McFarland, D. Hackett, eds., Triazine Herbicides: Risk Assessment, American Chemical Society Symposium Series vol. 683, p. 82-87.

DeSouza, M.L., M.J. Sadowsky, J. Seffernick, B. Martinez, and L.P. Wackett (1998) The atzABC genes encoding atrazine catabolism are widespread and highly conserved J. Bacteriol. 180:1951-1954.

Sadowsky, M.J., M.L. DeSouza, Z. Tong, and L.P. Wackett (1998) AtzC is a member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes J. Bacteriol. 180:152-158.

DeSouza, M.L., L.P. Wackett, and M.J. Sadowsky (1998) The genes encoding atrazine catabolism are located on a self-transmissable plasmid in Pseudomonas sp. ADP Appl. Environ. Microbiol. 64:2323-2326.

Wackett, L.P. (1998) Directed evolution of new enzymes and pathways for environmental biocatalysis Anal. NY Acad. Sci. 864:142-152.

Wackett, L. P. (1998) Microbial enzymes in biodegradation In R. Fass, Y. Flashner and S. Reuveny, Eds. Novel Approaches for Bioremediation of Organic Pollutants, Kluwer Academic Publishers, New York p. 95-103.

Lange, C.C., L.P. Wackett, K. Minton, and M. Daly (1998) Engineering a recombinant Deinococcus radiodurans for organopollutant degradation in radioactive mixed waste environments Nature Biotechnology 16:929-933.

Cai, Baoli, S. Vuilleumier, and L.P. Wackett (1998) Site-directed mutagenesis of the dichloromethane dehalogenase gene from Methylosinus strain DM11 Weishengwu Xuebao 38:163-167.

Cai, B., S. Vuilleumier and L. Wackett (1998) Purification and characterization of the mutant enzyme W117F of the dichloromethane dehalogenase of Methylophilus sp. strain DM11 Anal. NY Acad. Sci. 864:210-213.

Ellis, L.B.M., C.D. Hershberger and L.P. Wackett (1999) The University of Minnesota Biocatalysis/Biodegradation Database: Specialized metabolism for functional genomics Nucl. Acids Res. 27:373-376.

Wackett, L.P., L.B.M. Ellis, S.M. Speedie, C.D. Hershberger, H-J. Knackmuss, A.M. Spormann, C.T. Walsh, L.J. Forney, W.F. Punch, T. Kazic, M. Kanehisa, and D.J. Berndt (1999) Predicting microbial biodegradation pathways ASM News 65:87-93.

Wackett, L.P. and L.B.M. Ellis (1999) Biocatalysis databases Encyclopedia of Biotechnology, Academic Press, New York p. 260-267.

Wackett, L.P. and L.B.M. Ellis (1999) Predicting biodegradation Environ. Microbiol. 1:119-124.

Wackett, L.P. (2000) Environmental biotechnology Trends Biotechnol. 18:19-21.

Ellis, L.B.M., C.D. Hershberger and L.P. Wackett (2000) The University of Minnesota Biocatalysis/Biodegradation Database: Microorganisms, Genomics and Prediction Nucl. Acids Res. 28:377-379.

Strong, L.C., H. McTavish, M. J. Sadowsky, L. P. Wackett (2000) Field-scale remediation of atrazine-contaminated soil using recombinant Escherichia coli over-expressing atrazine chlorohydrolase Environ. Microbiol. 2:91-98.

Brim, H., S.C. McFarlan, J.K. Fredrickson, K.W. Minton, M. Zhai, L.P. Wackett and M.J. Daly (2000) Engineering Deinococcus radiodurans for metal remediation in radioactive mixed waste environments Nature Biotech. 15:85-90.

Venkateswaran A., S.C. McFarlan, D. Ghosal , K.W. Minton, A.Vasilenko, K. Makarova, L.P. Wackett, M.J. Daly (2000) Physiologic determinants of radiation resistance in Deinococcus radiodurans Appl. Environ. Microbiol. 66:2620-2626.

Wackett, L.P. and N.C. Bruce (2000) Environmental biotechnology. Towards sustainability. Curr. Op. Biotech. 11:229-231.

Seffernick, J.L., G. Johnson, M.J. Sadowsky, and L.P. Wackett (2000) Substrate specificity of atrazine chlorohydrolase and atrazine-catabolizing bacteria Appl. Environ. Microbiol. 66:4247-4252.

Liu, J., M. Viguroux, C.D. Hershberger, L.B.M. Ellis, L.P. Wackett, J.D. Varner (2000) Heuristic-based prediction of specialized metabolism. Intelligent Systems in Molecular Biology, University of California Press .

Sadowsky, M.J. and L. P. Wackett (2001) Genetics of atrazine degradation by Pseudomonas sp. strain ADP and other bacteria In: R.E. Haugland, R.M. Zablotowicz, and J. C. Hall (eds.), Pesticide Biotransformations in Plants and Microorganisms, American Chemical Society, Washington, DC p. 268-282.

Ellis, L.B.M., C. D. Hershberger, E. M. Bryan, and L. P. Wackett (2001) The University of Minnesota Biocatalysis/Biodegradation Database: Emphasizing Enzymes Nucl. Acids. Res. 29:340-343.

Wackett, L. P. (2001) The pathways of biodegradation In (M. Dworkin, S. Falkow, E. Rosenberg, K-H. Schleifer, E. Steckebrandt, Eds.) The Prokaryotes (in press) .

Liu, J., M.Vigouroux, C. D. Hershberger, L. B. M. Ellis, L. P. Wackett (2001) Heuristic-based prediction of specialized metabolic pathways. In Proceeding of the Ninth International Conference on Intelligent Systems in Molecular Biology, Copenhagen, Denmark .

Seffernick, J.L., de Souza M.L., Sadowsky M.J., Wackett L.P. (2001) Melamine deaminase and atrazine chlorohydrolase: 98 percent identical but functionally different J. Bacteriol. 183(8):2405-10.

Wackett, L.P. (2001) Antibiotics and antibiotic resistance in the environment Environ. Microbiol. 3(3):226-227.

Wackett L.P. (2001) Microbioal biofilms Environ. Microbiol. 3(2):144.

Wackett L.P. (2001) Microbes inside the Earth and potentially on other planetary bodies. An annotated selection of World Wide Web sites relevant to the topics in Environmental Microbiology Environ. Microbiol. 3(4):294-5.

Dunwell J., Wackett L.P., Gilardi G., Kost T.A., Condreay P., Projan S., Hugenholtz J., Kleerebezem M. (2001) Biotechnology Curr. Opin. Biotechnol. 12(3):221-226.

Wackett, L.P., M.J. Sadowsky, B. Martinez, N. Shapir (2001) Biodegradation of atrazine and related triazine compounds: From enzymes to field studies Appl. Microbiol. Biotechnol. (in press).

Raillard, S-A., A. Krebber, Y. Chen, J.E. Ness, E. Bermudez, R. Trinidad, R. Fullem, C. Davis, M. Welch, J. Seffernick, L.P. Wackett, W.P.C. Stemmer and J. Minshull (2001) Novel enzyme activities and functional plasticity revealed by recombining homologous enzymes Chem. Biol. 125:1-9.

Martinez, B., J. Tomkins, L.P. Wackett, R. Wing, and M.J. Sadowsky (2001) Complete nucleotide sequence and organization of the atrazine catabolic plasmid pADP-1 from Pseudomonas sp. ADP J. Bacteriol. 183:5684-5697.

Seffernick, J.L. and L.P. Wackett (2001) Rapid evolution of bacterial catabolic enzymes: A case study with atrazine chlorohydrolase Biochemistry 40:12747-12753.

Wackett, L.P., M.J. Sadowsky, B. Martinez, N. Shapir (2002) Biodegradation of atrazine and related triazine compounds: From enzymes to field studies Appl. Microbiol. Biotechnol. 58:39-45.

Sajjaphan, K., N. Shapir, A.K.Judd, L.P. Wackett and M.J. Sadowsky (2002) A novel psbA1 gene from a naturally-occurring atrazine-resistant cyanobacterial isolate Appl. Environ. Microbiol. 68:1358-1366.

Wackett, L.P. (2002) Expanding the map of microbial metabolism Environ. Microbiol. 4:12-13.

Handelsman, J. and L.P. Wackett (2002) Microbial diversity: Sustaining the earth and industry Curr. Op. Microbiol. 5:237-239.

Shapir N, Osborne JP, Johnson G, Sadowsky MJ, Wackett LP (2002) Purification, Substrate Range, and Metal Center of AtzC: the N-Isopropylammelide Aminohydrolase Involved in Bacterial Atrazine Metabolism J. Bacteriol. 184(19):5376-84.

Seffernick JL, Shapir N, Schoeb M, Johnson G, Sadowsky MJ, Wackett LP (2002) Enzymatic Degradation of Chlorodiamino-s-Triazine Appl. Environ. Microbiol. 68(9):4672-4675.

Parales, R.E., N.C. Bruce, A. Schmid and L.P. Wackett (2002) Biodegradation, Biotransformation and Biocatalysis Appl. Environ. Microbiol. 68:4699-4709.

Strong, L.C., C. Pedersen, M.J. Sadowsky, L.P. Wackett (2002) Arthrobacter aurescens TC1 metabolizes diverse s-triazine ring compounds Appl. Environ. Microbiol. 68:5973-5980.

Seffernick, J.L., H. McTavish, J.P. Osborne, M.L. de Souza, M.J. Sadowsky and L.P. Wackett (2002) Atrazine chlorohydrolase from Pseudomonas sp. strain ADP is a metalloenzyme Biochemistry 41:14430-14437.

Shapir, N., J.P. Osborne, G. Johnson, M.J. Sadowsky and L.P. Wackett (2002) Purification, substrate range and metal center of AtzC: The N-isopropylammelide hydrolase involved in bacterial atrazine metabolism. J. Bacteriol. 184:5376-5384.

Ellis, L.B.M., B.K. Hou, W. Kang and L.P. Wackett (2003) The University of Minnesota Biocatalysis/Biodegradation Database: Post genomic data mining. Nucl. Acids Res. 31:262-265.

Wackett, L.P. (2003) Pseudomonas putida - a versatile biocatalyst. Nature Biotech. 21:136-138.

Wackett, L.P. (2004) Applications of genomics to biocatalysis and biodegradation. In (C.M. Fraser, T. Read and K.E. Nelson, eds.) Microbial Genomes. The Human Press, Inc., Totowa, New Jersey, pp. 443-459 .

Wackett, L.P. (2003) Evolution of new enzymes and pathways: Soil microbes adapt to s-triazine herbicides. In:J. Gan, P.C. Zhu, S.D. Aust, and A.T. Lemley (eds.), Pesticide Decontamination and Detoxification, American Chemical Society Symposium Series No 863, Washington, DC, pp. 37-38 .

Fruchey, I., N. Shapir, M.J. Sadowsky and L.P. Wackett (2003) On the origins of cyanuric acid hydrolase: Purification, substrates and prevalence of AtzD from Pseudomonas sp. ADP. Appl. Environ. Microbiol. 69:3653-3657.

Hou, B.K., L.P. Wackett, and L.B.M. Ellis (2003) Microbial pathway prediction: A functional group approach. J. Chem. Inf. Comp. Sci. 43:1051-1057.

Negrete-Raymond, A.C., B. Weder, and L.P. Wackett (2003) Catabolism of arylboronic acids by Arthrobacter nicotinovorans strain PBA. Appl. Environ. Microbiol. 69:4263-4267.

Wackett, L.P., A.G. Dodge, and L.B.M Ellis (2004) Microbial genomics and the periodic table. Appl. Environ. Microbiol. 70:647-655.

Vetting, M.W., L.P. Wackett, L. Que Jr., J.D. Lipscomb, and D.H. Ohlendorf (2004) A crystallographic comparison of a manganese and an iron-dependent extradiol dioxygenase. J. Bacteriol. 186:1945-1958.

Wackett, L.P. (2004) Stable isotope probing in biodegradation research. Trends Biotechnol. 22:153-154.

Sajjaphan, K., N. Shapir, L.P. Wackett, M. Palmer, J. Tomkins, B. Blackmon, and M.J. Sadowsky (2004) The Arthrobacter aurescens TC1 atrazine catabolic genes trzN, atzB and atzC are linked on a 160 kb region and functional in E. coli. Appl. Environ. Microbiol. 70:4402-4407.

Wackett, L.P. (2004) Novel biocatalysis by database mining. Curr Op. Biotech. 15:280-284.

Hou, B.K., L.B.M. Ellis, and L.P. Wackett (2004) Encoding microbial metabolic logic: Predicting biodegradation. J. Ind. Microbiol. Biotechnol. 31:261-272.

Wackett, L.P. (2004) Evolution of enzymes for the metabolism of new chemical inputs in the environment. J. Biol. Chem. 279:41259-41262 (mini-review).

Strong, L.C. and L.P. Wackett (2005) Engineering of bioremdiation processes: A critical review. In (M. Fingerman, Ed) Bioremdiation for Aquatic and Terrestrial Ecosystems (in press).

Daly, M.J., E. K. Gaidamakova, V. Y. Matrosova, A. Vasilenko, M. Zhai, A. Venkateswaran, M. Hess, M. V. Omelchenko, H. M. Kostandarithes, K. S. Makarova, L. P. Wackett, J. K. Fredrickson, and D. Ghosal (2004) Accumulation of Mn(II) in Deinococcus radiodurans facilitates gamma-radiation resistance. Science 306:1025-1028.

Dodge, A.G. and L.P. Wackett (2005) Metabolism of bismuth subsalicylate and intracellular accumulation of bismuth by Fusarium sp. BI. Appl. Environ. Microbiol. 71:876-882.

Shapir, N, C. Rosendahl, G. Johnson, M. Andreina, M.J. Sadowsky and L.P. Wackett (2005) Substrate specificity and colorimetric assay for recombinant TrzN derived from Arthrobacter aurescens TC1. Appl. Environ. Microbiol. 71:2214-2220.

Ghosal, D., M.V. Omelchenko, V.Y. Matrosova, A. Vasilenko, E.K. Gaidamakova, M. Zhai, H.K. Kostandaithes, K.S. Makarova, L.P. Wackett, J.K. Fredrickson, and M.J. Daly (2005) How radiation kills cells: Survival of Deinococcus radiodurans and Shewanella oneidensis viewed from the perspective of systems that produce and defend against oxidative stress. FEMS Microbiol. Rev. 29:361-375.

Shapir, N.C., M.J. Sadowsky, and L.P. Wackett (2005) Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. ADP. J. Bacteriol 187:3781-3788.

Cheng, G., N. Shapir, M.J. Sadowsky, and L.P. Wackett (2005) Allophanate hydrolase, not urease, functions in bacterial cyanuric acid metabolism. Appl. Environ. Microbiol. 187:3731-3738.

Strong, L.C. and L.P. Wackett (2005) Engineering of bioremdiation processes: A critical review. In (M. Fingerman, Ed) Bioremdiation for Aquatic and Terrestrial Ecosystems (in press).

Wackett, L.P. and L.B.M. Ellis (2005) Biodegradation of organic pollutants. Nature Encyclopedia (in press).

Wang, L., D.A. Samac, N. Shapir, L.P. Wackett, C.P. Vance, and M.J. Sadowsky (2005) Biodegradation of atrazine in transgenic plants expressing a modified bacterial atrazine chlorohydrolase (atzA) gene. Plant Biotechnol. J. 3:475-486.

Emerson, J.P., Wagner, M.L., M.F. Reynolds, L.Que, Jr., M.J. Sadowsky, and L.P. Wackett (2005) The role of histidine-200 in MndD, the Mn(II)-dependent 3,4-dihydroxyphenylacetate 2,3-dioxygenase from Arthrobacter globiformis strain CM-2, a site-directed mutagenesis study. J. Bioinorg. Chem. 10:751-760.

Ellis, L.B.M., D. Roe, and L.P. Wackett (2006) The University of Minnesota Biocatalysis/Biodegradation Database: The first decade. Nucl. Acids Res. 34:D517-D521.

Shapir, N., G. Cheng, M.J. Sadowsky and L.P. Wackett (2006) Purification and characterization of TrzF: Allophanate hydrolases support growth on biuret. Appl. Environ. Microbiol. 72:2491-2495.

Brim, H., J. P. Osborne, V.Y. Matrosova, M. Zhai, A. Venkateswaran, H.M. Kostandarithes, J. K. Fredrickson, L.P. Wackett, and M. J. Daly. (2006) Deinococcus radiodurans engineered for complete toluene degradation facilitates Cr(VI) reduction. Microbiology 152: 2469-2477.

Shapir, N. C. Pedersen, O. Gil, L. Strong, J. Seffernick, M.J. Sadowsky and L.P. Wackett (2006) TrzN from Arthrobacter aurescens TC1 is a zinc amidohydrolase. J. Bacteriol. 188: 5859-5864.

Dodge, A.G., J.R. Richman, G. Johnson, and L.P. Wackett (2006) Thioamide metabolism by Ralstonia picketii TA. Appl. Environ. Microbiol. 72:7468-7476.

Mongodin, E.F., N. Shapir, S. C. Daugherty, R. T. DeBoy, J. Emerson, A. Shvartzbeyn, D. Radune, J. Vamathevan, V. Grinberg, H. Khouri, L. P. Wackett, K. E. Nelson, and M. J. Sadowsky (2006) Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1. PLOS Genetics 2: 20214-20220.

N. Shapir, E. F. Mongodin, M. J. Sadowsky, S. C. Daugherty, K. E. Nelson, and L. P. Wackett (2007) Evolution of catabolic pathways: genomic insights into microbial s-triazine metabolism. J. Bacteriol. 189:674-682.

Wackett, L.P. (2007) Pathways to discovering new microbial metabolism for functional genomics and biotechnology. Adv. Micro. Physiol. 61:219-232.

Seffernick, J.L., A. Aleem, J.P. Osborne, G. Johnson, M.J. Sadowsky and L.P. Wackett (2007) Hydroxyatrazine N-ethylaminohydrolase (AtzB): Characterization and insights into active site architecture of an amidohydrolase superfamily enzyme. J. Bacteriol. 189: 6989-6997.

Wackett LP, Frias JA, Seffernick JL, Sukovich DJ, Cameron SM. (2007) Genomic and biochemical studies demonstrating the absence of an alkane-producing phenotype in Vibrio furnissii M1. Appl Environ Microbiol. Nov;73(22):7192-8. PMID: 17921268 [PubMed - in process]

Wackett, L.P. (2008) Microbial-based motor fuels: Science and technology. Microbial Biotechnol. (e-pub ahead of print).

Wackett, L.P. (2008) Biomass to fuels via microbial transformations. Curr. Op. Chem. Bio. 12:1-7.

Wackett, L.P. and L.B.M. Ellis (2008) Mechanisms of degradation of synthetic chemicals. Handbook of Environmental Chemistry, published online March 14, 2008

Mandelbaum, R.T., M.J. Sadowsky, and L.P. Wackett (2008) Microbial degradation of s-triazine herbicides. In: H. LeBaron, J. McFarland, and O. Burnside (eds.), The Triazine Herbicides, Elsevier, Amsterdam.

Wackett, L.P. (2008) Microbial-based motor fuels: Science and technology. Microbial Biotechnol. 1: 211-225.

Gross, C., R. Felsheim, and L.P. Wackett (2008) Genes and enzymes of azetidine-2-carboxylate metabolism: Detoxification and assimilation of an antibiotic. J. Bacteriol. 190: 4859-4864.

Ellis, L.B.M., J. Gao, K. Fenner, and L.P. Wackett (2008) The University of Minnesota pathway prediction system: predicting metabolic logic. Nucl. Acids Res. 36:W427-W432.

Fenner, K., J. Gao, S. Kramer, L. Ellis, and L.P. Wackett (2008) Data-driven extraction of relative reasoning rules to limit combinatorial explosion in biodegradation pathway prediction. Bioinformatics 24: 2079-2085.

Frias, J.A., J.E. Richman, and L.P. Wackett (2009) C29 olefinic hydrocarbons biosynthesized by Arthrobacter species. Appl. Environ. Microbiol. (in press).