Nate's Page

Previous employment:

9/02 to 8/03 Post-doctoral research associate performing research on N.S.F. Young Investigator grant “Assessment of the utility of oligonucleotide microarrays for SNP detection in maize genomic DNA.”
7/00 to 9/02 Post-doctoral research associate performing research on N.S.F. Grant No. 9975930 “Functional genomics of chromatin global control of plant gene expression.”
7/97 to 7/00 - U.S.D.A. National Needs Fellow, University of Minnesota
9/95 to 5/97 - Undergraduate research assistant, Southeast Missouri State University
9/94 to 9/97 - Tutor, Southeast Missouri State University
6/96 to 8/96 - Undergraduate research program, Cold Spring Harbor Laboratory

A.A. with highest honors (1994): Bethany Lutheran College
B.S. with highest honors (1997): Biology Major, Southeast Missouri State University
Ph.D. (2000): Plant Biology, University of Minnesota

Awards and Academic honors:
National Merit Scholarship (1994)
Phi Kappa Phi (1996)
1997 U.S.D.A. National Needs Fellowship, University of Minnesota

Agro8230: Cytogenetics
PBIO5960: Epigenetic Mechanisms of Gene Regulation
BIOL4003: Genetics

Nathan M. Springer. (2000) Isolation of genes involved in epigenetic regulation and the inheritance of an aneuploid syndrome in maize. University of Minnesota.

8. Springer NM, Kaeppler SM. (2005) Evolutionary Divergence of Monocot and Dicot Methyl-CpG-Binding Domain Proteins. Plant Physiol. 138(1):92-104.
7. Till B.J., S.H. Reynolds, C. Weil, N.M. Springer, C. Burtner, C.A. Codomo, L.C. Enns, A.R. Odden, K. Young, E. Bowers, E.A. Greene, L. Comai, S. Henikoff . 2004. Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol. 4(1):12.
6. Plant functional genomics consortium. 2005. Transgene-induced RNA interference as a Tool for Plant Functional Genomics. In RNA Interference Methods in Enzymology eds. John Rossi and David Engelke. Methods Enzymol. 392:1-24.
5. Springer N. M., W. B. Barbazuk. 2004. Utility of different gene-enrichment approaches towards identifying and sequencing the maize gene space. Plant Physiol 136:3023-33.
4. Springer N.M., C.A. Napoli, D.A. Selinger, R. Pandey, K.C. Cone, V.L. Chandler, H.F. Kaeppler, S.M. Kaeppler. 2003. Comparative Analysis of SET Domain Proteins in Maize and Arabidopsis Reveals Multiple Duplications Preceding the Divergence of Monocots and Dicots. Plant Physiol. 132:907-925
3. Springer, N.M., O. Danilevskaya, P. Hermon, T. Helentjaris, R.L. Phillips, H.F. Kaeppler, S.M. Kaeppler. 2002. Sequence Relationships, Conserved Domains, and Expression Patterns for Zea mays Homologs of the Drosophila Polycomb Group Genes E(z), esc, and E(Pc). Plant Physiol. 128: 1332-1345
2. Papa, C.M., N.M. Springer, M.G. Muszynski, R. Meeley, and S.M. Kaeppler. 2001. Maize chromomethylase Zea methyltransferase2 is required for CpNpG methylation. Plant Cell 13: 1919-1928.
1. *Cao, X, N.M. *Springer, M.G. Muszynski, R.L. Phillips, S. Kaeppler, and S.E. Jacobsen. 2000. Conserved plant genes with similarity to mammalian de novo DNA methyltransferases. Proc. Natl. Acad. Sci. 9:4979-4984. *These authors contributed equally to this work

1. Kaeppler, S.M., N.M. Springer. 2002. Silence of the genes: Epigenetic gene silencing as a tool in genetic research and cultivar development. Proceedings of the 56th Annual Corn and Sorghum Research Conference.

36. Monde R; Till B, Mantick N, Hunding L, Young K, Laport R, Springer N, Hsia A, Dunham T, Schnable P, Neuffer G, Hake S, Henikoff S, Comai L, Weil C 2005. The Maize TILLING project: A progress report. 47th Maize Genetics Conference march 10-13, 2004. Lake Geneva, WI.
35. Cone K, McGinnis K, Chandler V, Springer N, Pikaard C, Dawe K, Kaeppler H, Kaeppler S, 2005. Functional genomics of maize chromatin. 47th Maize Genetics Conference march 10-13, 2004. Lake Geneva, WI.
34. Springer NM, Barbazuk, WB. 2005. Applications of oligonucleotide microarrays for polymorphism detection and comparative genomic hybridization. 47th Maize Genetics Conference march 10-13, 2004. Lake Geneva, WI. (Poster)
33. Springer N. M., 2004. Applications of oligonucleotide microarrays for polymorphism detection in maize. Texas A&M Linking genomics to crop improvement symposia. April 22, 2004. Invited speaker.
32. Cone, K.C., K.M. McGinnis, C.M. Napoli, N.M. Springer, N Kovacevic, H.F. Kaeppler, S.M. Kaeppler, V.C. Chandler. 2004. Chromatin Genes: Discovery, Mutagenesis, and Function. Maize Genetics Conference Abstracts. 46:P92. 46th Maize Genetics Conference. March 11-14, 2004 Mexico City, Mexico.
31. Springer, N.M., W. B. Barbazuk. 2004. A gene-centric approach to determine how close we are to sequencing the maize gene space. 46th Maize Genetics Conference. March 11-14, 2004. Mexico City, Mexico.
30. Springer, N. M., A. Thompson, S.M. Kaeppler. 2004. The Maize Polycomb Group Gene, Mez1, Shows Imprinted Expression Throughout Endosperm Development. Maize Genetics Conference Abstracts. 46:P102. 46th Maize Genetics Conference. March 11-14, 2004. Mexico City, Mexico.
29. Springer, N.M., S.M. Kaeppler. 2004. Optimizing Conditions for SNP Detection Using Oligonucleotide Microarrays. Maize Genetics Conference Abstracts. 46:P141. 46th Maize Genetics Conference. March 11-14, 2004. Mexico City, Mexico.
28. Zaunbrecher, V., N.M. Springer, S.M. Kaeppler.. 2004. Allelic Effects of Maize Chromomethylase Mutants on DNA Methylation Maize Genetics Conference Abstracts. 46:P105. 46th Maize Genetics Conference. March 11-14, 2004 Mexico City, Mexico.
27. Springer N. M., 2004. How does Mother know best? Searching for the molecular mechanisms that control imprinted gene expression. University of Minnesota Plant Biology Departmental Seminar. February 16th, 2004. Invited speaker.
26. Springer N. M., 2004. How does Mother know best? Searching for the molecular mechanisms that control imprinted gene expression. University of Minnesota Plant Biology Departmental Seminar. February 10th, 2004. Invited speaker.
25. Springer N.M., 2003. Evolution of chromatin gene families in plants. Donald Danforth Plant Sciences Center, St. Louis MO. November 4th, 2003. Invited speaker.
24. Springer N.M., Thompson A.R., Kaeppler S.M. 2003. Imprinted expression of the maize SET domain gene Mez1. Snowbird Plant Genetic Variation Conference. October 22-26th, Snowbird, UT.
23. Springer N.M. 2003. Assessment of the use of oligonucleotide microarrays for single nucleotide polymorphism detection in maize. Plant Genome Program Awardee meeting. September 18-19th 2003. Washington D.C.
22. Springer N.M, S.M. Kaeppler. 2003. Bioinformatic analysis of the plant methylation machinery. Gordon Research Conference on Epigenetics. August 10-15th, 2003. Holderness, NH.
21. Springer, N.M. 2003. Functional Genomic of maize chromatin. Purdue seminar series April 1, 2003. West Lafeyette, IN. Invited speaker.

20. McGinnis, K, V.C. Chandler, C.M. Napoli, H.F. Kaeppler, S.M. Kaeppler, N.M. Springer, K.C. Cone. 2003. Functional Genomics of Chromatin Genes in Maize. Maize Genetics Conference Abstracts 45:P28. 45th Maize Genetics Coorperative Meeting. March 13-17, 2002 Lake Geneva, WI.
19. Springer, N.M., S. M. Kaeppler. 2003. Applications of oligonucleotide microarrays for maize functional genomics. 45th Maize Genetics Coorperative Meeting. March 13-17, 2002 Lake Geneva, WI.
18. Kaeppler S.M., N.M. Springer. 2003. Maize Array Analysis Using the NimbleGen Maskless Array Synthesizer. Plant and Animal Genome Meeting. January 14-17th 2003 San Diego, CA.
17. Springer, N.M., H.F. Kaeppler, S.M. Kaeppler. 2002. Relationships among maize (Zea mays) and Arabidopsis SET domain proteins. 44th Maize Genetics Cooperative Meeting. March 17-21, 2002. Orlando, FL.
16. Springer, N.M. 2001. Epigenetic inheritance in plants: Exceptions to Mendel's Laws. Southeast Missouri State University. April 11, 2001. (Invited presentation)
15. Springer, N.M., C.M. Papa, M.G. Muszynski, O. Danilevskaya, P. Hermon, A. Smith, S. Kerns, R.L. Phillips, H.F. Kaeppler, S.M. Kaeppler. 2001. Analysis of genes encoding Polycomb group proteins in maize. 43rd Maize Genetics Cooperative Meeting. March 14-18, 2001. Lake Geneva, WI.
14. Springer, N.M., O. Danilevskaya, P. Hermon, A. Smith, T. Helentjaris, R.L. Phillips, H.F. Kaeppler, S.M. Kaeppler. 2001. Analysis of genes encoding Polycomb group proteins in maize. 43rd Maize Genetics Cooperative Meeting. March 14-18, 2001. Lake Geneva, WI.
13. Kerns, S.K., N.M. Springer, D. Selinger, L. Schmitt, H.F. Kaeppler, S.M. Kaeppler. 2001. Isolation of methyl-CpG-binding domain genes from maize. 43rd Maize Genetics Cooperative Meeting. March 14-18, 2001. Lake Geneva, WI.
12. Springer, N.M., C.M. Papa, M.G. Muszynski, R.L. Phillips, S.M. Kaeppler. 2000. DNA methyltransferase genes in maize: Synergies and differences from maize-Arabidopsis comparisons. Arabidopsis Genomics Conference. December 7-10, 2000. Cold Springer Harbor, NY.
11. Springer, N.M., S.M. Kaeppler, and R.L. Phillips. 2000. Epigenetic inheritance of an aneuploid induced phenotype. 42nd Maize Genetics Cooperative Meeting. March 16-19, 2000. Coure D’Alene, ID.
10. Springer, N.M., S.M. Kaeppler, and R.L. Phillips. 1999. Epigenetic inheritance of an aneuploid induced phenotype. Gordon Conference on Epigenetics. August 8-12, 1999. Holderness School, VT.
9. Springer, N.M., C.M. Papa, P.M. Olhoft, M.G. Muszynski, and S.M. Kaeppler. 1999. Characterization of DNA methyltransferases in maize. Gordon Conference on Epigenetics. August 8-12, 1999. Holderness School, VT.
8. Papa, C.M., M.G. Muszynski, N. Springer, and S.M. Kaeppler. 1999. Sequence and function of the maize methyltransferase, zmet2. 41st Maize Genetics Cooperative Meeting. March 13-15, 1999. Delavan, WI.
7. Springer, N.M., W. Lilly. 1997. Isolation of the proteasome complex from Schizophyllum commune. Southeast Missouri University Student Research Conference. April 29-30, 1997. Cape Girardeau, MO.
6. Springer, N.M., S. Hum-Musser, D.A. Starrett. 1997. Cloning and characterization of avocado alpha-galactosidase. Southeast Missouri University Student Research Conference. April 29-30, 1997. Cape Girardeau, MO.
5. Springer, N.M., D.A. Starrett. 1997. Fruit ripening: The use of biotechnology as a tool to alter the ripening process. Great Plains Honor Council. April 18-20, 1997. San Marcos, TX.
4. Springer, N.M., M. Timmermans, R.A. Martienssen. 1997. Specification of leaf shape and leaf cell identity in bladeless2 mutants of maize. 39th Annual Maize Genetics Cooperation Meeting. March 15-18, 1997. Clearwater Beach, FL.
3. Springer, N.M., D. A. Starrett. 1997. Biotechnology and fruit ripening. Honors Council of the Illinois Region Annual Conference. February 21-22, 1997. Elmhurst, IL.
2. Springer, N.M., D. A. Starrett, S. Hum-Musser. 1996. PCR amplification and cloning of Avocado Alpha-Galactosidase. Student Research Conference. April 22-23, 1996. Cape Girardeau, MO.
1. Springer, N.M., S. Hum-Musser, K.C. Gross, D. Starrett. 1996. Amplification and cloning of Avocado Alpha-Galactosidase. Missouri Academy of Science. April 19, 1996. Canton, MO.

Nathan Springer's Maize Genetics Lab

Dr. Nathan Springer