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Welcome to the website of BIOL 4003 Genetics... 
Meeting time and place: Monday Wednesday Friday, 1:55 - 2:45 in B35 Classroom-Office Building
Instructor: Dr. Jane Glazebrook [e-mail: jglazebr@umn.edu; Phone: 612-624-5194 ]
Office address: 324 Cargill Laboratory of Plant and Microbial Genomics
Office hours: Monday 10:00 – 11:00 and Thursday 1:00– 2:00 in Rm.324 Cargill
Teaching assistant: Wei-Shan Hsu [e-mail hsuxx066@umn.edu; Phone:
(612) 624-4966
]
Office hours: Monday 4:00-5:00 and Wednesday 11:00-12:00 in Rm 6-118 MCB
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The final exam key is posted under exams. The fourth page of the exam histograms shows the scores on the final. The last page shows the relatoinship between total points in the course and course grades. the course grades were entered at 12:30pm on Wednesday Dec 16, so they should be accessible by the afternoon of Thursday Dec 17. That's all for this year. Have a good break!
I've put copies of this year's exams without the key on the exams page. You may like to practice taking them again.
Final Help Sessions:
- Wei Shan: Wednesday December 10 4:00-5:30 Rm 3-120 MCB
- Dr. Glazebrook: Friday December 12 10:00-11:30 Rm 12(in the basement) BioSci Center St. Paul
Help sessions will not have any formal program. Come with questions and problems, and we will explain the answers.
Final Exam is SATURDAY DEC 13 1:30-3:30, in our usual classroom. YES, THAT IS THE SATURDAY RIGHT AFTER CLASSES END!
Our discussion of RNAi includes figures and concepts that are not in the book. To make this easier for you, I have posted my class notes, figures that are not from the book, and three references. you are not required to read the references, but you may find them helpful and/or interesting.
To read about creating mice with insertion mutations in particular genes (reverse genetics) by homologous recombination in embryonic stem cells, refer to pages 654-656 in Chapter 22, and look at Figure 22.28.
Exam #3 Help Sessions:
- Wei Shan: Wednesday November 19 4:00-5:30 Rm 3-120 MCB
- Dr. Glazebrook: Thursday November 20 4:00-5:30 Rm 365 Borlaug Hall St. Paul
Help sessions will not have any formal program. Come with questions and problems, and we will explain the answers.
For problem 16.26, use this site rather than the one in the book: http://blast.ncbi.nlm.nih.gov/Blast.cgi. Click on "protein blast".
A practice problem for genetic and physical mapping is here. The answer is here. Please add this to your list of homework problems.
Would you like to get some experience working in a Genetics lab? A colleague has an opening for a part-time position (5-10 hours per week). Details here.
Slides that Dr. Springer showed that are not figures from the textbook are here.
How are you doing? To estimate your course grade so far, add your points from Exam 1, points from Exam 2, and 10 extra points. Divide this number by 225 (points so far). If you have 85% or more, you are looking at an A, 75% to 85%, at least a B, 60% to 75%, at least a C, 45% to 60%, at least a D.
A practice bacterial 3-point problem is here. The answer is on the second page.
The set of 3-point cross problems for our chromsome map is here.
Errors in the textbook:
- Chapter 3: In the answer to problem 3.3, the second term of the chi-squared test is incorrect. It should be (72-67)2 / 67. In the study guide, there is a mistake in the answer to problem 3.9 part c. There are 8 F1 gametes from the triple heterozygote, not 4 as stated in the study guide. The answer in the back of the textbook is correct. In the Study Guide, the answer to 3.20a is incorrect. It should be 6 x (1/2)2(1/2)2. Page 55, first line of the second column, says "Because each probability is (3/4)4(1/4)...." It should read (3/4)3.
- Chapter 4: In the Study guide, the answer to 4.4(a) should be S1S3, S2S3. In the Study guide, in the answer to problem 4.8 part c: Turquoise is only ctct.
- Chapter 7: The Study guide has a misprint in the answer to 7.14. In the table, the gametes from plant I should be DP (0.4), dp (0.4), dP (0.1) and Dp (0.1). The genotypes of the gametes are also wrong in the first part of the answer.
- Chapter 8: The distance from A to B on the map on page 199 should be 12.5 cM. In problem 8.27, there are a total of 102 tetrads in the first cross, not 100 as shown.
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