Stanley Dagley Lectureship Series

Background

Stanley Dagley was Regents Professor of Biochemistry at the University of Minnesota. Known for his luminary teaching, Professor Dagley was also highly regarded for his research on microbial oxidation reactions. Dagley first studied microbial biochemistry from a thermodynamics standpoint with Chemistry Nobel Laureate Sir Cyril Hinshelwood at Oxford. He started his professorial career at the University of Leeds prior to his distinguished tenure at the University of Minnesota.

Professor Stanley Dagley inspired a legion of scientists to investigate novel and exotic microbial biochemistry using simple, but elegant, biochemical logic. Some of those he inspired have initiated the Stanley Dagley Lectureship.

Stanley Dagley, Regents Professor of Biochemistry, BMBB faculty 1970-1987

2022: Dr. Daniel Herschlag

From structure-function to ensemble-function: A needed paradigm shift

Professor of Biochemistry
Stanford University; Stanford, California

2021: Dr. David R. Liu

Base Editing and Prime Editing: GenomeEditing Without Double-Strand Breaks

Professor of Chemistry and Chemical Biology
Harvard University; Boston, MA
Title: Base Editing and Prime Editing: GenomeEditing Without Double-Strand Breaks

2020: Dr. Jon Clardy

Chasing Molecules and Mechanisms in the Gut Microbiome

Harvard Medical School
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology

Archive

Year	Speaker/Affiliation	Title
2019	Dr. Craig A. Townsend Alsoph H. Corwin Professor of Chemistry Johns Hopkins University, Baltimore, MD	New Insights into Enediyne Antitumor Antibiotic Biosynthesis
2018	Dr. Patricia C. Babbitt Professor of Bioengineering & Therapeutic Science University of California-San Francisco, San Francisco, CA	Evolution of new enzymes from privileged ancestral scaffolds
2017	Dr. Andrew D. Ellington Fraser Professor of Biochemistry, Center for Systems and Synthetic Biology, University of Texas at Austin, Austin, TX	Feedback loops in directed evolution
2016	Dr. Christina Smolke Professor of Bioengineering, Schools of Engineering & Medicine, Stanford University, Stanford, CA	Synthetic biology platforms for natural product biosynthesis and discovery
2015	Dr. Donald Hilvert Professor of Chemistry, Swiss Federal Institute of Technology Zürich (ETH), Swizerland	Nearer to nature: design and optimization of artificial enzymes Self-assembling, subercharged protein containers
2014	Dr. Pamela Silver Elliot T. and Onie H. Adams Professor of Biochemistry and Systems Biology, Harvard Medical School, Boston, MA	Biology is the technology of this century Designing biological systems for health and sustainability
2013	Dr. Dan S. Tawfik Professor, Department of Biological Chemistry, The Weizmann Institute of Sciences, Rehovolt, Israel	Promiscuity, noise and the divergence of new protein functions The ongoing expansion of protein sequence space
2012	Dr. Frances H. Arnold (Nobel Laureate) Dick and Barbara Dickinson Professor of Chemical Engineering, Bioengineering & Biochemistry, California Institute of Technology	Design by evolution: engineering biology in the 21st century Enzyme engineering by structure-guided recombination
2011	Dr. Jack Szostak (Nobel Laureate) Center for Computational and Integrative Biology, Harvard Medical School, Boston, MA	The Origin of Cellular Life Towards Self-Replicating Genetic Polymers
2010	Dr. John Roth University of California, Davis, CA	A molecular view of natural selection: Understanding high-speed adaptation. Pathways of genetic change: Three stories about gene copy number changes.
2008	Dr. Stephen Withers University of British Columbia, Vancouver, BC, Canada	Sugars are good for you: their roles as therapeutics. Engineering and evolution of old enzymes for new tasks: glycoside assembly.
2007	Dr. Gregory A. Petsko Brandeis University; Waltham, MA (Adjunct Professor, Harvard Medical School)	Structural Enzymology in Four Dimensions: Time-Resolved Crystal Structures of Enzymes At Work. The Next Epidemic: What Happens To Your Brain As You Get Older and What We're Trying To Do About It.
2006	Dr. Peter G. Schultz The Scripps research Institute, La Jolla, CA	An expanding genetic code. Synthesis at the interface of chemistry and biology.
2005	Dr. Perry Frey University of Wisconsin, Madison	A story of hydrogen bonding: The low-barrier hydrogen bond in chymotrypsin. Science and Antiscience.
2004	Sir David Hopwood John Innes Centre, Norwich, UK	The discovery and development of antibiotics. Using Streptomyces genes to make new antibiotics.
2003	Dr. Rolf Thauer Max Plank Institute, Germany	On Methanogens and Methanotrophs. Biochemistry of Methanogenesis.
2002	Dr. Arthur Kornberg (Nobel Laureate) Stanford University School of Medicine	Reflections on DNA Replication and Current Studies on Inorganic Polyphosphate. Biotechnology: Academia and/or Business.
2001	Dr. Daniel Koshland, Jr. University of California, Berkeley	Propagation of Conformational Changes in Receptors and Enzymes. Scientific Advances: What Will We be Able To Do and What Will We Be Allowed To Do?