Department of Biochemistry, Molecular Biology and Biophysics
Structural Biology & Biophysics
FACULTY AND RESEARCH INTERESTS | |
Primary Members | |
Molecular mechanisms of DNA rearrangement/recombination reactions | |
Multinuclear magnetic resonance techniques; metalloproteins/metal homeostasis; Alzheimer's Disease. | |
Oxygenase mechanisms, metalloproteins, magnetic resonance techniques, kinetics. | |
Protein structure; RNA structure; Protein-RNA, DNA interaction; Enzyme kinetics. | |
Cell adhesion; protein-protein/carbohydrate interactions. | |
Protein engineering; structural biology; x-ray crystallography; molecular biology. | |
Molecular dynamics in muscle. | |
Structure and dynamics of membrane embedded enzymes. | |
Targeted protein degradation; Protein quality control; NMR spectroscopy. | |
Structural enzymology: Metal ions & organic co-factors; Human disease: cardiovascular, Alzheimers. | |
Secondary Members | |
Biological networks that coordinate metabolism and growth. | |
Diabetes, metabolite sensing and signaling, metabolic enzyme regulation. | |
Joint Members - From Other Departments | |
Que, Jr., Lawrence | Active site structures and mechanisms of nonheme iron enzymes; trapping of reactive intermediates, design and synthesis of functional metalloenzyme models and chiral oxidation catalysts; artificial DNA hydolysis agents. |
