Department of Biochemistry, Molecular Biology and Biophysics
Molecular Biology
The main focus of the Molecular Biology Division is to understand the regulation of basic and disease related cellular processes such as gene expression, hormonal signaling, RNA processing, DNA replication, recombination and repair.
FACULTY AND RESEARCH INTERESTS | |
Primary Members | |
Gene structure and regulation | |
Regulation of DNA replication, cell cycle, cancer | |
Molecular mechanisms of plant-pathogen interactions and plant gene expression | |
Mechanisms of purposeful mutation relating to innate and adaptive immunity | |
Division Head | Mechanisms of mammalian DNA double-strand break repair |
Gene expression; protein phosphorylation cascades. | |
Genome stability, mutation; DNA replication, repair and genetic recombination. | |
Eukaryotic molecular biology; hormone action; gene expression. | |
Nucleic acid biochemistry; molecular genetics. | |
Cellular mechanisms of maintaining genomic stability; DNA damage response during chromosomal replication. | |
Nutritional and hormonal regulation of mammalian gene expression. | |
Secondary Members | |
Mechanism of insulin action; regulation of gene expression by lipids; lipid transporters and lipid binding proteins; obesity and metabolic regulation. | |
Biological networks that coordinate metabolism and growth | |
Signal Transduction, Natriuretic Peptides, Guanylyl Cyclase Receptors and cGMP. | |
Nucleic acid biochemistry; molecular biology. | |
Joint Members - From Other Departments | |
Regulation of gene expression; cancer | |
Determination of the animal body plan; patterning of the eye; biochemical properties of auto-processing systems | |
Cytoskeleton and cell motility; Developmental mechanisms | |
Role of protein tyrosine phosphatases in cell differentiation and cell adhesion | |
Cerebellar gene expression; mammalian development; histocompatability genes | |
Temporal control of development; gene expression; protein-DNA interactions | |
Molecular biology of animal development; gene expression; protein-protein and protein-DNA interactions | |
Sex determination; regulation of gene expression in development | |
