An exchange procedure for the regulatory light chain of skeletal muscle myosin:

Measuring ATPase activity as an indicator of restored muscle function

Abstract

A procedure for successfully extracting the regulatory light chain (RLC) of

skeletal muscle myosin and reconstituting it with modified RLC would enable

new research for understanding structural changes that occur during muscle

contraction. This work describes an exchange procedure showing promising

results as measured by calcium dependence of ATPase activity on homogenized

myofibrils that muscle function is restored compared to the control.