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Frederick J. Bollum Endowed Research Fund for Biochemistry Lectureship Series
The 12th Annual Bollum Symposium
Wednesday, May 5th, 2010
Background
Frederick J. Bollum received a B.A. in Zoology in 1949 and a Ph.D. in Physiological
Chemistry in 1956 from the University of Minnesota. He went on to a Postdoctoral
Fellowship at the Universtiy of Wisconsin and then took a position at Oak Ridge
National Laboratory in Tennessee. Later, he became a Professor of Biochemistry
at the University of Kentuchy Medical School, in Lexington, KY and then Chairman
of Biochemistry at Uniformed Services University for the Health Sciences, Bethesda,
MD. He then moved on to become President and CEO of Supertechs, Inc., Biotechnology
Consultants. His major research interests were nucleic acid chemistry and enzymology,
nucleotide metabolism, genetic aspects of biochemistry, immunological diversification
and recombinant DNA, authoring more than 260 papers and three books.
Dr. Bollum regularly contributes to the Department of Biochemistry, Molecular
Biology and Biophysics through the Minnesota Medical Foundation. His gifts have
helped support lectures, research, graduate student awards and meeting opportunities
and an annual symposium on cutting edge research topics.
| Year/Topic |
Speaker/Affiliation |
Titles |
1999
Transcription Factors & Metabolic Control |
Gretchen J. Darlington, Baylor College of Medicine
Steven A. Kliewer, Glaxo-Wellcome Research & Develoment
Timothy S. Osborne, University of California, Irvine |
The Role of C/EBP Proteins in Integratie Metabolism
PPARs and PXR: Orphan Nuclear Receptors that Define Novel Hormone Signaling Pathways.
Positive and Negative Regulation of Genes that Regulate Cholesterol Metabolism. |
2000
G Protein-Coupled Signaling |
Nigel Bunnett, University of California, San Francisco
Linda Hicke, Northwestern University
John Tesmer, University of Texas
David Clapham, Harvard Medical School |
How Proteases Talk to Cells: A Comparison of Signaling by Proteases and Neuropeptides
Role of Ubiquitin in Signaling Receptor Downregulation
Effector Regulation by Heterotrimeric G Proteins: Lessons Learned from Adenyl Cyclase
Protein Gated Potassium Channels |
2001
Directed Evolution of Biomolecules & Functional Genomics |
Dr. Jeremy Minshull, Maxygen
Dr. Karl Dane Wittrup, Massachusetts Institute of Technology
Dr. George Georgiou, University of Texas
|
Biological Diversity: From Nature and Beyond.
Engineering Protein Recognition, Stability, and Expression by Yeast Display
Functional Expression of Multidisulfide Proteins in
Bacteria: Genetic, Biochemical, Structural Biology and Directed Evolution Strategies. |
2002
Nature's Copier: the DNA Replication Machinery |
Dr. Melvin DePamphilis, National Institute of Child Health and Human Development
Dr. Bik-Kwoon Tye, Cornell University
Dr. James Berger, University of California, Berkeley
|
The ORC Cycle: a Novel Mechanism for Regulating Eukaryotic DNA Replication
Coordination of Genome Expression and DNA Replication in Proliferating Cells: The Multiple Roles of the MCM Proteins in Eukaryotes
Toward a Structural Understanding of DNA Replication Initiation |
2003
Structural Dymamics of Membrane Signal Transduction |
Dr. Wayne Hubbell, Jules Stein Eye Institute, UCLA
Dr. Lynmarie Thompson, University of Massachusetts, Amherst
Dr. John Spudich, University of Texas, Houston
Dr. David Farrens, Oregon Health and Science University |
A nitroxide's view of rhodopsin structure, dynamics and activation
Site-directed solid-state NMR probing transmembrane signaling mechanisms in bacterial chemoreceptors.
Microbial rhodopsins: structure/function in ion transport and signaling.
Conformational changes in G-protein coupled receptors: insights gained from site-directed fluorescence studies. |
2004
Proteomics: Advancing Our Understanding of Biology |
Michel Desjardins, Université de Montréal
Tim Haystead,Duke University Medical Center
Kathryn E. Howell
University of Colorado School of Medicine, Denver
Bradford W. Gibson
Buck Institute of Aging Research
|
Proteomics Brings New Paradigms to Immunology
Proteome Mining Drug and Target Discovery en Masse.
New Insights into Golgi Function Through Proteomics
The Mitochondrial Proteome, Neurodegenerative Disease and Aging |
2005
Computational Biochemistry and Molecular Biology
(program) |
Dr. Eric D. Siggia, Rockefeller University in New York
Dr. Peter D. Karp, Stanford Research Institute International (SRI), Palo Alto (CA)
Dr. Michael A. Savageau, University California, Davis.
Dr. Jiali Gao, University of Minnesota
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Computation Approaches to Blastoderm Patterning in the Fly and its Evolution.
Databases and Algorithms for Pathway Bioinformatics.
System Design Principles and Construction of Gene Circuits Dynamics, Pathways, and Tunneling: A Computational Perspective of Enzyme Catalysis |
2006
The Science of Aging
(program)
|
Dr. Leonard P. Guarante, MIT, Boston
Dr. Holly Van Remmen, University of Texas, San Antonio
Dr. Richard A. Miller, University of Michigan
Dr. Richard Weindruch, University of Wisconsin |
SIR2, Calorie Restriction and Aging
Fifty Years of the Oxidative Stress Theory of Aging: Where Are We Now?
Fifty Years of the Oxidative Stress Theory of Aging: Where Are We Now?
Size, Stress, and Aging: Lessons from Dwarf Mice
Caloric Restriction and Aging: Studies in Mice and Monkeys |
2007
Reguating Biological Function by Ubiquitination
(program) |
Dr. Rachel Klevit, University of Washington, Seattle, WA
Dr. Keith D. Wilkinson, Emory University School of Medicine, Atlanta, GA
Dr. Daniel Finley, Harvard Medical School, Boston, MA
Dr. Randy Hampton, University of California, San Diego, La Jolla, CA
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Recognition and Disassembly of the Polyubiquitin Targeting Signal.
Structural Insights into Diversity and specificity in Protein Ubiquitination.
Regulation of Protasome Activity.
Protein Quality Control in Cell Regulation. |
2008
Circadian Clocks
(program) |
Dr. Steve A. Kay, University of California, San Diego
Dr. Amita Sehgal, HHMI/ University of Pennsylvania Medical School
Dr. Joseph S. Takahashi, HHMI/Northwestern University
Dr. Ying-Hui Fu, University of California, San Francisco |
Network Discovery Pipelines for Circadian Clocks.
Molecular Biology of Circadian Rhythms in Drosophila.
Genetic Analysis of Circadian Clocks in Mammals.
Molecular Characterization of Human Sleep Variants.
|
2009
The Biochemistry of Biofuels |
Dr. Timothy Donohue, University of Wisconsin-Madison
Dr. Jay Keasling, University of California, Berkeley
Dr. James C. Liao, University of California, Los Angeles
Dr. Stephen Ragsdale, University of Michigan, Ann Arbor |
Tapping into Microbial Genomes for Light-driven Hydrogen Production.
Engineering Microorganisms for Production of Advanced Biofuels.
Fuels and Chemical Beyond Petroleum.
Nickel Enzymes in the Biochemistry of Biofuels.
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