PUBLICATIONS (2000 - )

1. C. Schmidt-Dannert(2000) Engineering novel carotenoids in microorganisms. Curr. Opin. Biotechnol. 11:255-261. PMID:10851142
2. C. Schmidt-Dannert, D. Umeno and F.H. Arnold (2000) Molecular breeding of carotenoid biosynthetic pathways. Nature Biotechnol. 18:750-753. PMID:10888843
   
3. P. C. Traub, C. Schmidt-Dannert, J. Schmitt and R.D. Schmid (2001) Gene synthesis, expression in E. coli, and in vitro refolding of Pseudomonas sp. KWI56 and Chromobacterium viscosum lipases and their chaperones. Appl. Microbiol. Biotechnol. 55:198-204. PMID: 11330714
   
4. A.M.F. Liu, N.A. Somers, R.J. Kazlaukas, T.S. Brush, F. Zocher, M.M. Enzelberger, U.T. Bornscheuer, G.P.Horsman, A. Mezetti, C. Schmidt-Dannert and R.D. Schmid (2001) Mapping the substrate selectivity of new hydrolases using colorimetric screening: lipases from Bacillus thermocatenulatus and Ophiostoma piliferum, esterases from Pseudomonas fluorescens and Streptomyces diastatochromogenes. Tetrahedron: Assymetry 12:545-556.
   
5. S. Lange, A. Musidlowska, C. Schmidt-Dannert, J. Schmitt and U.T. Bornscheuer (2001) Cloning, functional expression and characterization of recombinant pig liver esterase. ChemBioChem 2:576-582. PMID: 11828491
   
6. Kauffman and C. Schmidt-Dannert (2001) Conversion of Bacillus thermocatenulatus lipase into an efficient phospholipase with increased activity towards long chain fatty acyl substrates by directed evolution and rational design. Protein Eng. 14:919-928. PMID: 11742112
   
7. C. Schmidt-Dannert (2001) Directed evolution of single proteins, metabolic pathways and viruses. Biochemistry 44:13125-13136. PMID:11683620
   
8. P.C. Lee and C. Schmidt-Dannert (2002) Metabolic engineering towards biotechnological production of carotenoids in microorganisms. Appl. Microbiol. Biotechnol., 60:1-11. PMID: 12382037
   
9. A.L. deBoer and C. Schmidt-Dannert (2003) Recent efforts in engineering microbial cells to produce new chemical compounds. Curr. Opin. Chem. Biol. 7:273-278. PMID: 12714061
   
10. P.C. Lee, A.Z.R. Momen, B. Mijts and C. Schmidt-Dannert (2003) Biosynthesis of structurally novel carotenoids in Escherichia coli. Chem. Biol. 10:452-463. PMID: 12770827
    
11. S.J. Kwon, A. deBoer, R. Petri, C. Schmidt-Dannert (2003) High-level production of porphyrins in metabolically engineered E. coli: Systematic extension of a pathway assembled from overexpressed genes involved in heme biosynthesis. Appl. Environ. Microbiol. 69:4875-4882. PMID: 12902282
    
12. B.N. Mijts, C. Schmidt-Dannert (2003) Engineering of secondary metabolic pathways. Curr. Opin. Biotechnol. 14:597-602. PMID: 14662388
    
13. K. Watts, P.C. Lee and C. Schmidt-Dannert (2004) Exploring recombinant flavonoid biosynthesis in metabolically engineered Escherichia coli. ChemBioChem. 5:500-507. PMID: 15185374
    
14. R. Petri and C. Schmidt-Dannert (2004) BioCyc-Genome and Metabolism. Angew. Chem. Int. Ed. 43:1908.
    
15. Petri and C. Schmidt-Dannert (2004) Dealing with complexity: Evolutionary engineering and genome shuffling. Curr. Opin. Biotechnol. 5:298-304. PMID: 15296928
    
16. S.J. Kwon, R. Petri, A.L. de Boer and C. Schmidt-Dannert (2004) A high-throughput screen for metal chelatases: Application to the directed evolution of ferrochelatases for metalloporphyrin biosynthesis. ChemBiochem. 5:1069-1074. PMID: 15300829
    
17. P.C. Lee, B.N. Mijts and C. Schmidt-Dannert (2004) Investigation of factors influencing production of the monocyclic carotenoid torulene in metabolically engineered Escherichia coli. Appl. Microb. Biotechnol. 65:538-46. PMID: 15168092
    
18. P.C. Lee, R. Petri, B.N. Mijts, K.T. Watts and C. Schmidt-Dannert (2004) Alteration of product specificity of Aeropyrum pernix farnesylgeranyl diphosphate synthase (Fgs) by directed evolution. Protein Eng. Des. Sel. 17:771-7. PMID: 15548566
    
19. B. Mijts, P.C. Lee and C. Schmidt-Dannert (2004) Engineering carotenoid biosynthetic pathways. Meth. Enzymol. 388:315-329. PMID: 15289080
    
20. P.C. Lee, R. Petri, B. N. Mijts, K.T. Watts and C. Schmidt-Dannert (2005) Directed evolution of Escherichia coli farnesyl diphosphate synthase (IspA) reveals novel determinants of chain length specificity. Metab. Eng.7:18-26. PMID: 15721807
    
21. B. Mijts, P.C. Lee and C. Schmidt-Dannert (2005) Identification of a carotenoid oxygenase synthesizing novel acyclic carotenoids: combinatorial biosynthesis and directed evolution. Chem. Biol. 12:1-8. PMID: 1585098
    
22. B. Ku, J.C. Jeong, B.N. Mijts, C. Schmidt-Dannert, J.S. Dordick (2005)

    Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. Appl. Environ Microbiol. 71:6578-83. PMID: 1626968
23. K.T. Watts, P.C.Lee, and C.Schmidt-Dannert (2006) Biosynthesis of plant- specific stilbene polyketides in metabolically engineered Escherichia coli. BMC Biotechnol. Mar 21;6:22. PMID: 1655136
24. E.K. Marasco, K.Vay, and C. Schmidt-Dannert (2006) Identification of carotenoid cleavage dioxygenases from Nostoc sp. PCC 7120 with different cleavage activities. J Biol Chem. 281(42):31583-93. PMID: 16920703
25. K.T. Watts, B.N. Mijts, P.C. Lee, A.J. Manning, and C. Schmidt-Dannert (2006) Discovery of a substrate selectivity switch in tyrosine ammonia-lyase, a member of the aromatic amino acid lyase family.Chem Biol. Dec;13(12):1317-26. PMID: 17185227
26. E. Holtzapple and C. Schmidt-Dannert (2007) Biosynthesis of isoprenoid wax ester in Marinobacter hydrocarbonoclasticus DSM 8798: identification and characterization of isoprenoid coenzyme A synthetase and wax ester synthases. J Bacteriol. 189(10):3804-12 PMID:17351040