Research Papers
- MacDuff, D., M.S. Neuberger & RS Harris (2005) MDM2 can interact with the
C-terminus of AID but it is inessential for antibody diversification in DT40
B cells. Molecular Immunology, in press. PubMed
Link
- Schumacher, A.J., D.V. Nissley & RS Harris (2005) APOBEC3G hypermutates
genomic DNA and inhibits Ty1 retrotransposition in yeast. Proceedings of the
National Academy of Sciences USA, 102, 9854-9859. PubMed
Link
- Haché, G, M.T. Liddament & RS Harris (2005) The retroviral hypermutation
specificity of APOBEC3F and APOBEC3G is governed by the C-terminal DNA cytosine
deaminase domain. Journal of Biological Chemistry, 280, 10920-10924. PubMed
Link
- Liddament, M. T., Brown, W. L., Schumacher, A. J., and Harris, R. S. (2004).
APOBEC3F properties and hypermutation preferences indicate activity against
HIV-1 in vivo. Curr Biol 14, 1385-1391. PubMed
Link
- Beale, R. C., Petersen-Mahrt, S. K., Watt, I. N., Harris, R. S., Rada, C.,
and Neuberger, M. S. (2004). Comparison of the differential context-dependence
of DNA deamination by APOBEC enzymes: correlation with mutation spectra in
vivo. J Mol Biol 337, 585-596. PubMed
Link
- Conticello, S. G., Harris, R. S., and Neuberger, M. S. (2003). The Vif protein
of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G.
Curr Biol 13, 2009-2013. PubMed
Link
- Harris, R. S., Bishop, K. N., Sheehy, A. M., Craig, H. M., Petersen-Mahrt,
S. K., Watt, I. N., Neuberger, M. S., and Malim, M. H. (2003). DNA deamination
mediates innate immunity to retroviral infection. Cell 113, 803-809.
PubMed
Link
- Harris, R. S., Petersen-Mahrt, S. K., and Neuberger, M. S. (2002). RNA editing
enzyme APOBEC1 and some of its homologs can act as DNA mutators. Molecular
Cell 10, 1247-1253. PubMed
Link
- Petersen-Mahrt, S. K., Harris, R. S., and Neuberger, M. S. (2002). AID mutates
E. coli suggesting a DNA deamination mechanism for antibody diversification.
Nature 418, 99-103. PubMed
Link
- Harris, R. S., Sale, J. E., Petersen-Mahrt, S. K., and Neuberger, M. S.
(2002). AID is essential for immunoglobulin V gene conversion in a cultured
B cell line. Current Biology 12, 435-438. PubMed
Link
Review Articles
- Harris, R. S., and Liddament, M. T. (2004). Retroviral restriction by APOBEC
proteins. Nature Reviews Immunology 4, 868 -877. Link
to Nature Reviews Immunology website.
- Harris, R. S., Sheehy, A. M., Craig, H. M., Malim, M. H., and Neuberger,
M. S. (2003). DNA deamination: not just a trigger for antibody diversification
but also a mechanism for defense against retroviruses. Nat Immunol 4,
641-643. PubMed
Link
- Neuberger, M. S., Harris, R. S., Di Noia, J., and Petersen-Mahrt, S. K.
(2003). Immunity through DNA deamination. Trends in Biochemical Sciences
28, 305-312. PubMed
Link