Course Information
PURPOSE: The course Microbial Genomics and Bioinformatics is an introduction to genomics with an emphasis on developments in microbial genomics.
TOPICS: The topics to be covered are sequencing methodologies, sequence analysis, genomics databases, information theory and statistics, protein and DNA structure, proteomics and the genomes of model microbes.
OUTCOMES: Upon completion of the course, students will have acquired the knowledge to:
1. Search and use databases to access the most current genomics-related data,
2. Obtain DNA or protein sequence information and make comparisons,
3. Discuss the major prokaryotes genome sequencing projects objectives and
findings,
4. Appreciate the value of comparative genomics to develop new insights,
5. Apply genomics to address questions in microbial evolution,
6. Appreciate the role of horizontal gene transfer in shaping genomes,
7. Understand the seminars of industrial scientists who show genomics data,
8. Read papers on deducing protein function from gene sequence,
9. Understand general issues in proteomics
TEXTBOOK: Class book: Ussery, et al, Computing for Comparative Microbial Genomics, Springer, ISN+BN 978-84800-354-8; Note: You can purchase the book, or access it on-line for free through the University of Minnesota Library website
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